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Neurological (nerve and brain) diseases: The nervous system (the body's system of nerves) plays a vital part in achieving and maintaining an erection and it is common for men with diseases such as stroke, multiple sclerosis (MS), Alzheimer's disease, Parkinson's disease and spinal cord injuries to experience ED. This is due to an interruption in the transmission of nerve impulses between the brain and the penis.
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A psychosocial examination using an interview and questionnaire may reveal psychological factors contributing to erectile dysfunction. The sexual partner also may be interviewed to determine expectations and perceptions encountered during sexual intercourse.
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Of the 147 men seen, 141 had expressed an option when asked about their willingness-to-pay (WTP) for treatment. Thirty men (21.3%) wanted ED treatment completely free of charge (i.e., on the NHS), 100 (70.9%) wanted it free, but were willing to pay some cost if required to do so and 11 (7.8%) felt that it was inappropriate for ED to be treated in the NHS and were willing to pay for it 'at cost'. Following treatment with sildenafil, those who failed to have better erections were not willing to pay any amount, while in those who succeeded there were no statistically significant changes i.e. the 3 WTP groups did not show any significant upward or downward trend following success with sildenafil therapy.
What might be the cause for my or my partner's ability to achieve only brief or partial erections?
Apomorphine is a sublingual agent that is not approved by the US Food and Drug Administration (FDA). Apomorphine has a central effect on the hypothalamus. It is a D1/D2 dopamine receptor agonist from the apomorphine (nonopiate) drug class. This agent has been shown to specifically activate c-fos gene expression in the paraventricular and supraoptic nuclei of the hypothalamus in animal models. These areas are known to be involved with penile erections.
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In their latest study, the Wake Forest researchers first used standard biopsy techniques to harvest smooth-muscle and blood-vessel cells from the penises of healthy adult male rabbits. In the lab, the researchers used these cells to "seed" a special nutrient-rich collagen matrix. Over time, the cells multiplied within this framework to grow into new penile tissue.
One drawback to the use of these external vacuum devices is the need to assemble the equipment and the difficulty in transporting it. Many patients lose interest in using the device because of the preparations that are necessary, the lack of easy transportability, the inability to hide the tension ring, and the relative lack of spontaneity. Approximately half the men who use a vacuum device obtain very good erections, but only half of these men consistently use the device for a prolonged period.
"Animal studies have already indicated that you may be able to achieve as much or more with a single dose of radiation than with a protracted course," Scardino noted. "So, the big question is, are you going to find more complications as a result of this kind of a shift in dosage? Now, cutting back from seven and a half weeks to five weeks is a slight move in this direction, but they found no difference in sexual side effects, and that's valuable. And I certainly think we'll be seeing a lot more research in this area."
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FRIDAY, Dec. 5 (HealthDay News) -- A diagnosis of prostate cancer may prompt an understandable feeling of dread, but patients actually have a wide array of options at their disposal for tackling the disease, medical experts say.
In October 2007, the Food and Drug Administration (FDA) approved important changes to the drug labeling information for these medications. Selective enzyme inhibitors may be associated with a potential risk for sudden hearing loss, which may be accompanied by ringing in the ears (tinnitus) and dizziness (vertigo). Patients who experience sudden hearing loss in one or both ears while taking these medications for ED should stop taking the drug and contact a health care provider.
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